06072020Sun
Last updateFri, 15 May 2020 8am

vol.24-3

Gastroesophageal reflux disease: Evidence for influence on sleep and quality of life

Chien-Lin Chena, William C. Orrb

a Department of Medicine, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
b Lynn Institute for Healthcare Research, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

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Abstract
This review addresses current advances in gastroesophageal reflux disease (GERD) and its influence on sleep and health-related quality of life (QOL). Sleep difficulties are highly prevalent among adults with GERD, especially those who experience nighttime symptoms. These sleep difficulties result in substantial costs to the health care system by increasing provider visits. Because continued sleep disruption leads to increased daytime sleepiness and fatigue, nocturnal heartburn can reduce work productivity, as well as reduce function when performing normal daily activities. The continued presence of nocturnal symptoms in routine medical treatment is strongly associated with decreases in health-related quality of life. There is a greater loss of productivity to the employer and poorer health-related QOL (HRQOL) for the patient. Obstructive sleep apnea syndrome and obesity seem to predispose some patients to nocturnal GERD, and the presence of either of these conditions may help to identify patients with symptoms consistent with GERD. Appropriate management of GERD must include treatment of nighttime reflux symptoms that affect difficulty in both initiating and maintaining sleep.

Keywords
Gastroesophageal reflux disease; Health related quality of life; Sleep


 

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a Institute of Pharmacology and Toxicology, College of Medicine, Tzu Chi University, Hualien, Taiwan
b Department of Emergency Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
c Institute of Medical Sciences, College of Medicine, Tzu Chi University, Hualien, Taiwan
d Center of Vascular Medicine, College of Life Sciences, Tzu Chi University, Hualien, Taiwan
e Department of Medical Research, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
f Department of Pediatrics, Tzu Chi University, Hualien, Taiwan
g Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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Surgical treatment for proximal humeral fracture in elderly patients with emphasis on the use of intramedullary strut allografts

Cheng-Huan Penga, Wen-Tien Wua, b, Tzai-Chiu Yua, b, Li-Chun Chenc, Shih-Hsiang Hsua, b, Sai-Tung Kwonga, Ting-Kuo Yaoa, Kun-Chi Wua, b, Po-Chou Shaoa, Jen-Hung Wangd, Ing-Ho Chena, b

a Department of Orthopedics, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
b School of Medicine, Tzu Chi University, Hualien, Taiwan
c Department of Physical Medicine and Rehabilitation, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
d Department of Medical Research, Buddhist Tzu Chi General Hospital, Hualien, Taiwan

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Trend changes in the proportion of minimal invasive hysterectomies over a five-year period: A single-center experience

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a Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
b Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan
c Department of Pediatrics, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan

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Bilateral communicating coronary arteriovenous fistulas presenting with recurrent angina

Chiu-Fen Yanga, d, Shu-Hsin Liub, d, Jing-Ren Jengc, d, Michael Yu-Chih Chenc, d

a Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
b Department of Nuclear Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
c Department of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
d Department of Cardiology, Tzu Chi University, Hualien, Taiwan

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Feasibility of genetic testing for tuberous sclerosis in a 13-year-old boy

Chun-Ying Wenga, Shao-Yin Chua, b, c, Pei-Chun Laia, b, Lang-Yao Chend, Anyi Chend, Yi-Ning Sud, Pen-Jung Wanga, b

a Department of Pediatrics, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
b Department of Medicine, Tzu Chi University, Hualien, Taiwan
c Department of Medical Education, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
d Department of Medical Genetics, National Taiwan University Hospital, Taipei, Taiwan

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Effectiveness of rater consensus training in objective structured clinical examination using Kolb’s experiential learning

Shao-Yin Chua, b, Yu-Ling Lanc, Sheng-Po Kaoa, b, Tsung-Ying Chena, b, Ming-Chen Hsieha, b

a Department of Medical Education, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
b Department of Medicine, College of Medicine, Tzu Chi University, Hualien, Taiwan
c Department of Counseling and Clinical Psychology, National Dong Hwa University, Hualien, Taiwan

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