Anju Dinkara, Jitendra Singhb*
aDepartment of Microbiology, Institute of Medical Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India, bDepartment of Medicine, Narayana Medical College, Sasaram, Bihar, India
Open Access funded by Buddhist Compassion Relief Tzu Chi Foundation
Abstract
Objective: Recently, an alarming rise of dengue has been seen in India which remains a major public health concern. This study has been designed for a comprehensive overview of the epidemiology, gender, age, area distribution, symptomology, and seasonal variability. Materials and Methods: Retrospective analysis of 900 suspected dengue cases of all age groups of either sex from 2012 to 2017 at a North Indian tertiary care hospital revealed 461 (51.22%) cases seropositive for dengue. Results: The age group of 20–30 years was the most affected group with male predominance. The urban population was more affected as 75.05%, and maximum cases were detected in October month followed by November. Common abnormal laboratory parameters were thrombocytopenia (99.1%), hepatic dysfunction (59%), and leukopenia (26.68%). Two uncommon findings, pancytopenia and pancreatic dysfunction were reported in 7 and 3 cases respectively. Conclusion: Dengue infection in India has evolved rapidly, and regular outbreaks have been observed with a changing epidemiology, as the disease is rapidly spreading from urban to rural areas with increasing atypical manifestations.
Keywords: Atypical presentation, Dengue virus, Pancytopenia, Platelet transfusion, Vector-borne disease
