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Individualizing medical treatment of overactive bladder

Hann‑Chorng Kuoa,b*

aDepartment of Urology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, bDepartment of Urology, School of Medicine, Tzu Chi University, Hualien, Taiwan

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Open Access funded by Buddhist Compassion Relief Tzu Chi Foundation



Overactive bladder (OAB) syndrome is highly prevalent in both men and women and might have negative impact on quality of life. Clinical trials of OAB usually highly select participants that may not reflect the real‑world practice of OAB patients. The spectrum of OAB includes patients with idiopathic, neuropathic, with bladder outlet obstruction, and patients in elderly and medical comorbidities. Patients might have poor response to OAB medication or have adverse events after treatment. Therefore, treatment of OAB should be individualized to obtain therapeutic efficacy and avoid unacceptable adverse events. This article reviews the recently published literature and provides a guide for physicians to choose the appropriate treatment for different OAB patients.

Keywords: Bladder, Efficacy, Side effect, Urinary incontinence

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