Hsien‑Yi Yanga, Bor‑Cherng Sub, Ming‑Jay Hwangc, Yi‑Pang Leea,d*
aDepartment of Dentistry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, bDepartment of Pathology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan, cDepartment of Pathology, School of Medicine, Tzu Chi University, Hualien, Taiwan, dDepartment of Health Administration, Tzu Chi University of Science and Technology, Hualien, Taiwan
Open Access funded by Buddhist Compassion Relief Tzu Chi Foundation
Abstract
Fibrous dysplasia (FD) is a rare bony disorder in which normal bone is replaced by abnormal fibro‑osseous tissue. It often involves the long bones, craniofacial bones, ribs, and pelvis. Approximately 30% of monostotic FD (MFD) lesions are found in the cranial or facial bones. In general, FD is found in teenagers, and it usually becomes static after adulthood. FD involves the maxilla almost two times more often than the mandible. It frequently appears in the posterior region of the jaw bone and is usually unilateral. Here, we present an unusual case of symptomatic MFD affecting the anterior region of the mandible in a 43‑year‑old female with the clinical, radiographical, and histopathological features. The clinical examination showed both the labial and lingual bone expansion in the anterior mandible. The radiographic examination revealed a lesion with both radiopaque and radiolucent features showing a “ground‑glass” appearance. The diagnosis was obtained after confirmatory intrabony biopsy with the histopathological examination, and it was diagnosed with benign FD. The patient preferred regular follow‑up of MFD after discussion. During the regular follow‑up, MFD lesion showed no obvious signs of progression or malignancy features.
Keywords: Fibrous dysplasia, Mandible, Middle‑aged person, Monostotic
