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Last updateWed, 27 Mar 2024 6am

Symmetrical peripheral gangrene in sepsis after treatment with inotropes

Jiin‑Ling Jianga*, Lin‑Wei Tsenga, Huai‑Ren Changb

aDepartment of Nursing, Tzu Chi University, Hualien, Taiwan, bDepartment of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan

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Open Access funded by Buddhist Compassion Relief Tzu Chi Foundation

 

Abstract
Symmetrical peripheral gangrene (SPG) is characterized by sudden onset of peripheral, frequently symmetrical, gangrene in the absence of major vascular occlusive disease. We report a case of four limb SPG caused by septic shock with disseminated intravascular coagulation (DIC) that had been treated with inotropes. This case shows that SPG may be present as a complication of sepsis due to systematic derangement that affects a wide range of organ systems, including coagulation and microcirculation. Early recognition and prompt management of sepsis and optimization of the process of weaning off the inotropes at the earliest opportunity are necessary to avoid SPG.


Keywords: Inotropes, Sepsis, Symmetrical peripheral gangrene

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