Qian-Sheng Ke, Hann-Chorng Kuo
Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Abstract
Objective
To correlate between the overactive bladder symptom score (OABSS) and urgency severity score (USS) in a group of patients with over-active bladder (OAB) syndrome and evaluate the changes in these two measures after antimuscarinic treatment.
Materials and Methods
A total of 170 patients with clinical symptoms of frequency urgency were prospectively enrolled in this study. The Chinese version of the OABSS questionnaire, which has been linguistically validated, and the USS based on a 3-day voiding diary were recorded at baseline. Patients with clinically diagnosed OAB were treated with solifenacin 5 mg daily for 1 month, and the OABSS and USS were repeated at 1 week and 1 month. The OABSS and USS were compared at baseline, 1 week and 1 month after treatment.
Results
The patients enrolled included 98 men and 72 women with a mean age of 64.1 years. A high OABSS total score was significantly associated with a high grade of USS. There was a significant correlation between the two sores (R2=0.5520, p<0.0001). The main contributions to the OABSS in patients with a low USS were daytime frequency and nighttime frequency. The contribution of urgency and urgency urinary incontinence became significant in patients with high urgency grades. The changes in the USS and OABSS were significant at 1 month. The change in frequency was significant in the daytime as well as at nighttime.
Conclusion
A strong correlation between the OABSS and USS based on a voiding diary was noted in patients with OAB. The changes in these two measures were similar after solifenacin treatment.
Keywords
Lower urinary tract symptoms; Overactive bladder; Symptom score
